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Journal of Analytical Methods in Chemistry
Volume 2014, Article ID 368682, 4 pages
Research Article

Quantitative Analysis of Matrine in Liquid Crystalline Nanoparticles by HPLC

Guangdong Medical College, Xincheng Avenue, Guangdong 523808, China

Received 5 January 2014; Revised 31 March 2014; Accepted 1 April 2014; Published 14 April 2014

Academic Editor: Juan F. Garcia-Reyes

Copyright © 2014 Xinsheng Peng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A reversed-phase high-performance liquid chromatographic method has been developed to quantitatively determine matrine in liquid crystal nanoparticles. The chromatographic method is carried out using an isocratic system. The mobile phase was composed of methanol-PBS(pH6.8)-triethylamine (50 : 50 : 0.1%) with a flow rate of 1 mL/min with SPD-20A UV/vis detector and the detection wavelength was at 220 nm. The linearity of matrine is in the range of 1.6 to 200.0 μg/mL. The regression equation is (). The average recovery is 101.7%; %  (). This method provides a simple and accurate strategy to determine matrine in liquid crystalline nanoparticle.