Journal of Analytical Methods in Chemistry / 2014 / Article / Tab 1

Research Article

Studies on the Anti-Inflammatory Effect and Its Mechanisms of Sophoridine

Table 1

The results of SRI inhibited the production of IL-6 and IL-8 in LPS-stimulated mouse peritoneal macrophages and HL-60 cells .

GroupIL-6IL-8
OD value (mean ± SD)Inhibition (%)Content (ng/mL) (mean ± SD)Inhibition (%)

Blank 1.408 ± 0.050(2)20.2700 ± 1.3110(2)
LPS (5  g/mL)1.627 ± 0.01339.9700 ± 2.6230
LPS + SRI (1 × 10−8)1.508 ± 0.0797.313.910 ± 2.474(2)65.2
LPS + SRI (1 × 10−7)1.436 ± 0.09911.713.230 ± 1.167(2)66.9
LPS + SRI (1 × 10−6)1.431 ± 0.081(1)12.07.787 ± 1.910(2)80.5

Compared with LPS, (1) , (2) .