Simple and Sensitive Analysis of Blonanserin and Blonanserin C in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry and Its Application

Table 2

Extraction recovery, matrix effect, precision, and accuracy of the developed method (𝑛=6).

Analytes	QC Conc. (ng·mL^−1)	Extraction recovery (%)	Matrix effect (%)	Intraday (R.S.D, %)	Interday (R.S.D, %)	Accuracy (%)
Blonanserin	0.023	85.04±9.84	110.6±3.45	6.41	7.19	98.71
	0.23	95.21±5.49	112.8±4.17	2.96	4.98	101.2
	4.62	89.95±2.26	105.3±4.35	4.05	3.69	97.06
Blonanserin C	0.046	91.40±6.41	105.9±4.28	4.34	5.41	98.49
	0.46	86.15±11.82	110.5±13.39	3.50	5.37	101.7
	9.25	89.00±2.58	96.22±4.57	4.05	4.52	97.76