Simple and Sensitive Analysis of Blonanserin and Blonanserin C in Human Plasma by Liquid Chromatography Tandem Mass Spectrometry and Its Application

Table 3

Stability of the three analytes in rats plasma under different storage conditions (𝑛=5).

Analytes	QC Conc.; (ng·mL^−1)	Short term; (5 h, 25°C)	Autosampler; 25°C for 24 h	Three freeze-thaw cycles	Long term; (60 days, −20°C)
Blonanserin	0.023	4.52	1.01	−12.77	2.94
	0.23	4.52	−2.60	−0.95	8.13
	4.62	0.42	−2.54	−4.70	−1.31
Blonanserin C	0.046	−7.12	−2.16	−10.79	−2.08
	0.46	2.25	0.07	−8.20	8.08
	9.25	−3.34	−0.36	−9.46	−1.68

Stability values are represented as R.E. (%) = [Found Conc. − QC Conc.]/QC Conc. × 100%.