Simultaneous Determination of Cortisol and Cortisone from Human Serum by Liquid Chromatography-Tandem Mass Spectrometry

Table 2

Mean concentrations (ng/mL) of cortisol and cortisone in serum collected between 9:00 and 11:00 a.m.

	Mean age	Cortisol (range)	Cortisone (range)	Cortisone/cortisol ratios	P value
Male (𝑛=6)	52.3	132.9 (93.4–162.0)	27.8 (18.3–35.8)	0.209
Female (𝑛=43)	35.2	134.0 (46.1–267.0)	31.0 (14.1–55.7)	0.231
Total (𝑛=49)	37.3	133.9	30.5	0.225	𝑃<0.0001