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Journal of Analytical Methods in Chemistry
Volume 2015, Article ID 137489, 8 pages
http://dx.doi.org/10.1155/2015/137489
Research Article

Single-Round Patterned DNA Library Microarray Aptamer Lead Identification

1Human Effectiveness Directorate, 711 Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, Dayton, OH 45433, USA
2The Henry M. Jackson Foundation for the Advancement of Military Medicine, 6720A Rockledge Drive, Bethesda, MD 20817, USA
3Materials and Manufacturing Directorate, Air Force Research Laboratory, Wright-Patterson Air Force Base, OH 45433, USA
4UES Inc., 4401 Dayton-Xenia Road, Dayton, Dayton, OH 45433, USA

Received 12 November 2014; Revised 22 April 2015; Accepted 27 April 2015

Academic Editor: Chih-Ching Huang

Copyright © 2015 Jennifer A. Martin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The Supplementary Material provides additional information on data and methods supporting the Results and Discussion. Initial library pattern design and analysis, sequences and secondary structures of oligonucleotides from Figure 1, analysis of sequence motifs, random oligonucleotide fluorescence intensity measurements and sequences, and surface plasmon resonance sensorgrams are all included in Supplementary Material.

  1. Supplementary Material