Response Surface Optimization of a Rapid Ultrasound-Assisted Extraction Method for Simultaneous Determination of Tetracycline Antibiotics in Manure

Figure 3

Response surfaces using the Box-Behnken design obtained by plotting: (a) solution pH versus solution volume (extraction temperature: 30°C), (b) solution pH versus extraction temperature (solution volume: 40 mL), and (c) solution volume versus extraction temperature (solution pH: 7).

(a)

(b)

(c)