Development of a Gradient HPLC Method for the Simultaneous Determination of Sotalol and Sorbate in Oral Liquid Preparations Using Solid Core Stationary Phase

<div>Significance of mobile phase buffer pH controlling in SOT/SACC separation; pharmaceutical formulation F4 (1.000 mL of pharmaceutical preparation diluted to 25.00 mL); injection volume 5 <i>μ</i>L; mobile phase flow 1.3 mL min<sup>−1</sup>; linear gradient (ACN: 10% to 60% in 4 minutes); UV/Vis detector wavelength 237 nm; column oven 25°C.</div>

Journal of Analytical Methods in Chemistry

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Figure 1: Development of a Gradient HPLC Method for the Simultaneous Determination of Sotalol and Sorbate in Oral Liquid Preparations Using Solid Core Stationary Phase 

Figure 1 | Development of a Gradient HPLC Method for the Simultaneous Determination of Sotalol and Sorbate in Oral Liquid Preparations Using Solid Core Stationary Phase 