Improved Chiral Separation of (R,S)-Goitrin by SFC: An Application in Traditional Chinese Medicine

Table 1

Chromatographic data for separation of (R,S)-goitrin on Chiralpak IC column with different concentration of acetonitrile as cosolvent (column temperature: 35°C, flow rate: 3.5 mL/min, and back pressure: 100 bar).

Concentration (%)	Retention time (min)		Resolution
	S-goitrin	R-goitrin
20	1.95	2.15	1.76
15	3.04	3.48	3.78
10	5.99	7.14	3.86
8	9.15	11.02	4.41
7	11.66	14.08	4.16