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Journal of Analytical Methods in Chemistry
Volume 2016 (2016), Article ID 9752735, 8 pages
http://dx.doi.org/10.1155/2016/9752735
Research Article

Analyses of Total Alkaloid Extract of Corydalis yanhusuo by Comprehensive RP × RP Liquid Chromatography with pH Difference

1College of Life Science, Tarim University, Alar, Xinjiang 843300, China
2Key Laboratory of Protection and Utilization of Biological Resources in Tarim Basin of Xinjiang Production and Construction Corps, Alar, Xinjiang 843300, China

Received 12 May 2016; Revised 13 July 2016; Accepted 16 August 2016

Academic Editor: Rongda Xu

Copyright © 2016 Xiaodong Wei et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. D. O'Hagan, “Pyrrole, pyrrolidine, pyridine, piperidine and tropane alkaloids,” Natural Product Reports, vol. 17, no. 5, pp. 435–446, 2000. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Ziegler and P. J. Facchini, “Alkaloid biosynthesis: metabolism and trafficking,” Annual Review of Plant Biology, vol. 59, pp. 735–769, 2008. View at Publisher · View at Google Scholar · View at Scopus
  3. D. Cook, D. R. Gardner, and J. A. Pfister, “Swainsonine-containing plants and their relationship to endophytic fungi,” Journal of Agricultural and Food Chemistry, vol. 62, no. 30, pp. 7326–7334, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. X. L. Gao, D. Cook, M. H. Ralphs et al., “Detection of swainsonine and isolation of the endophyte Undifilum from the major locoweeds in Inner Mongolia,” Biochemical Systematics and Ecology, vol. 45, pp. 79–85, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. M. H. Pittler and E. Ernst, “Dietary supplements for body-weight reduction: a systematic review,” American Journal of Clinical Nutrition, vol. 79, no. 4, pp. 529–536, 2004. View at Google Scholar · View at Scopus
  6. D. G. Lalloo, D. Shingadia, G. Pasvol et al., “UK malaria treatment guidelines,” Journal of Infection, vol. 54, no. 2, pp. 111–121, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. S. Saxena, N. Pant, D. C. Jain, and R. S. Bhakuni, “Antimalarial agents from plant sources,” Current Science, vol. 85, no. 9, pp. 1314–1329, 2003. View at Google Scholar · View at Scopus
  8. G. Kai, C. Wu, L. Gen, L. Zhang, L. Cui, and X. Ni, “Biosynthesis and biotechnological production of anti-cancer drug Camptothecin,” Phytochemistry Reviews, vol. 14, no. 3, pp. 525–539, 2015. View at Publisher · View at Google Scholar · View at Scopus
  9. J. S. Liu, Y. L. Zhu, C. M. Yu et al., “The structures of huperzine-A and huperzine-B, 2 new alkaloids exhibiting marked anticholinesterase activity,” Canadian Journal of Chemistry-Revue Canadienne De Chimie, vol. 64, no. 4, pp. 837–839, 1986. View at Publisher · View at Google Scholar
  10. R. Wang, H. Yan, and X.-C. Tang, “Progress in studies of huperzine A, a natural cholinesterase inhibitor from Chinese herbal medicine,” Acta Pharmacologica Sinica, vol. 27, no. 1, pp. 1–26, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Feng, Z. F. Wang, X. C. He et al., “Bis-huperzine B: highly potent and selective acetylcholinesterase inhibitors,” Journal of Medicinal Chemistry, vol. 48, no. 3, pp. 655–657, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. J. Yan, L. Sun, G. Wu et al., “Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives,” Bioorganic & Medicinal Chemistry, vol. 17, no. 19, pp. 6937–6941, 2009. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Ding, B.-F. Sun, and G.-Q. Lin, “An efficient total synthesis of (−)-huperzine A,” Organic Letters, vol. 14, no. 17, pp. 4446–4449, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. M. Friedman and R. Rasooly, “Review of the inhibition of biological activities of food-related selected toxins by natural compounds,” Toxins, vol. 5, no. 4, pp. 743–775, 2013. View at Publisher · View at Google Scholar · View at Scopus
  15. E. Rytel, G. Lisińska, and A. Tajner-Czopek, “Toxic compound levels in potatoes are dependent on cultivation methods,” Acta Alimentaria, vol. 42, no. 3, pp. 308–317, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Kino, H. Hatanaka, M. Hashimoto et al., “FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics,” Journal of Antibiotics, vol. 40, no. 9, pp. 1249–1255, 1987. View at Publisher · View at Google Scholar · View at Scopus
  17. S. L. Ingram, “Pain: novel analgesics from traditional Chinese medicines,” Current Biology, vol. 24, no. 3, pp. R114–R116, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. Y.-T. Yu, H.-Y. Wei, H. Y. Fadamiro, and L. Chen, “Quantitative analysis of alkaloidal constituents in imported fire ants by gas chromatography,” Journal of Agricultural and Food Chemistry, vol. 62, no. 25, pp. 5907–5915, 2014. View at Publisher · View at Google Scholar · View at Scopus
  19. A. Akhgari, I. Laakso, T. Seppänen-Laakso et al., “Determination of terpenoid indole alkaloids in hairy roots of Rhazya stricta (Apocynaceae) by GC-MS,” Phytochemical Analysis, vol. 26, no. 5, pp. 331–338, 2015. View at Publisher · View at Google Scholar · View at Scopus
  20. X. Y. Chen, Y. X. Tang, S. Y. Wang, Y. P. Song, F. X. Tang, and X. P. Wu, “Field-amplified sample injection in capillary electrophoresis with amperometric detection for the ultratrace analysis of diastereomeric ephedrine alkaloids,” Electrophoresis, vol. 36, no. 16, pp. 1953–1961, 2015. View at Publisher · View at Google Scholar · View at Scopus
  21. J. M. Hagel, R. Mandal, B. Han et al., “Metabolome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants,” BMC Plant Biology, vol. 15, no. 1, article 220, 2015. View at Publisher · View at Google Scholar · View at Scopus
  22. A. Schenk, B. Siewert, S. Toff, and J. Drewe, “UPLC TOF MS for sensitive quantification of naturally occurring pyrrolizidine alkaloids in Petasites hybridus extract (Ze 339),” Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, vol. 997, pp. 23–29, 2015. View at Publisher · View at Google Scholar · View at Scopus
  23. Y. L. Song, N. Zhang, S. P. Shi et al., “Large-scale qualitative and quantitative characterization of components in Shenfu injection by integrating hydrophilic interaction chromatography, reversed phase liquid chromatography, and tandem mass spectrometry,” Journal of Chromatography A, vol. 1407, pp. 106–118, 2015. View at Publisher · View at Google Scholar · View at Scopus
  24. R. E. Murphy, M. R. Schure, and J. P. Foley, “Effect of sampling rate on resolution in comprehensive two-dimensional liquid chromatography,” Analytical Chemistry, vol. 70, no. 8, pp. 1585–1594, 1998. View at Publisher · View at Google Scholar · View at Scopus
  25. A. van der Horst and P. J. Schoenmakers, “Comprehensive two-dimensional liquid chromatography of polymers,” Journal of Chromatography A, vol. 1000, no. 1-2, pp. 693–709, 2003. View at Publisher · View at Google Scholar · View at Scopus
  26. P. J. Marriott, Z. Y. Wu, and P. Schoenmakers, “Nomenclature and conventions in comprehensive multidimensional chromatography—an update,” LC GC Europe, vol. 25, no. 5, pp. 266–275, 2012. View at Google Scholar · View at Scopus
  27. D. Li, C. Jakob, and O. Schmitz, “Practical considerations in comprehensive two-dimensional liquid chromatography systems (LCxLC) with reversed-phases in both dimensions,” Analytical and Bioanalytical Chemistry, vol. 407, no. 1, pp. 153–167, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. C. T. Scoparo, L. M. de Souza, N. Dartora, G. L. Sassaki, P. A. J. Gorin, and M. Iacomini, “Analysis of Camellia sinensis green and black teas via ultra high performance liquid chromatography assisted by liquid–liquid partition and two-dimensional liquid chromatography (size exclusion × reversed phase),” Journal of Chromatography A, vol. 1222, pp. 29–37, 2012. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Gilar, P. Olivova, A. E. Daly, and J. C. Gebler, “Two-dimensional separation of peptides using RP-RP-HPLC system with different pH in first and second separation dimensions,” Journal of Separation Science, vol. 28, no. 14, pp. 1694–1703, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. D. R. Stoll, K. O'Neill, and D. C. Harmes, “Effects of pH mismatch between the two dimensions of reversed-phase×reversed-phase two-dimensional separations on second dimension separation quality for ionogenic compounds—I. Carboxylic acids,” Journal of Chromatography A, vol. 1383, pp. 25–34, 2015. View at Publisher · View at Google Scholar · View at Scopus
  31. C. G. Horváth and S. R. Lipsky, “Peak capacity in chromatography,” Analytical Chemistry, vol. 39, no. 14, p. 1893, 1967. View at Publisher · View at Google Scholar · View at Scopus
  32. Y. N. Zhang, L. Zeng, C. Pham, and R. D. Xu, “Preparative two-dimensional liquid chromatography/mass spectrometry for the purification of complex pharmaceutical samples,” Journal of Chromatography A, vol. 1324, pp. 86–95, 2014. View at Publisher · View at Google Scholar · View at Scopus
  33. D. V. McCalley, “Effect of organic solvent modifier and nature of solute on the performance of bonded silica reversed-phase columns for the analysis of strongly basic compounds by high-performance liquid chromatography,” Journal of Chromatography A, vol. 738, no. 2, pp. 169–179, 1996. View at Publisher · View at Google Scholar · View at Scopus
  34. C. R. Wang, Z. M. Guo, Z. Long, X. L. Zhang, and X. M. Liang, “Overloading study of basic compounds with a positively charged C18 column in liquid chromatography,” Journal of Chromatography A, vol. 1281, pp. 60–66, 2013. View at Publisher · View at Google Scholar · View at Scopus
  35. J. K. Lee, J. G. Cho, M. C. Song et al., “Isolation of isoquinoline alkaloids from the tuber of Corydalis turtschaninovii and their inhibition activity on low density lipoprotein oxidation,” Journal of the Korean Society for Applied Biological Chemistry, vol. 52, no. 6, pp. 646–654, 2009. View at Publisher · View at Google Scholar
  36. X.-Y. Cheng, Y. Shi, S.-L. Zheng, W. Jin, and H. Sun, “Two new protoberberine quaternary alkaloids from Corydalis yanhusuo,” Journal of Asian Natural Products Research, vol. 10, no. 12, pp. 1117–1121, 2008. View at Publisher · View at Google Scholar · View at Scopus
  37. C. Wang, Z. Guo, J. Zhang, J. Zeng, X. Zhang, and X. Liang, “High-performance purification of quaternary alkaloids from Corydalis yanhusuo W. T. Wang using a new polar-copolymerized stationary phase,” Journal of Separation Science, vol. 34, no. 1, pp. 53–58, 2011. View at Publisher · View at Google Scholar · View at Scopus
  38. H.-T. Xiao, J. Peng, Y. Liang et al., “Acetylcholinesterase inhibitors from Corydalis yanhusuo,” Natural Product Research, vol. 25, no. 15, pp. 1418–1422, 2011. View at Publisher · View at Google Scholar · View at Scopus
  39. T. T. Trinh, K. Franke, A. Porzel, L. Wessjohann, and V. Tran, “Quaternary protoberberine alkaloids from Stephania rotunda,” Journal of Chemistry, vol. 44, no. 2, 2006. View at Google Scholar
  40. B. Ding, T. Zhou, G. R. Fan, Z. Y. Hong, and Y. T. Wu, “Qualitative and quantitative determination of ten alkaloids in traditional Chinese medicine Corydalis yanhusuo W.T. Wang by LC–MS/MS and LC–DAD,” Journal of Pharmaceutical and Biomedical Analysis, vol. 45, no. 2, pp. 219–226, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. T. T. Hu, X. Zhang, S. Z. Ma, and X. S. Yao, “A new protoberberine alkaloid from Corydalis yanhusuo W. T. Wang,” Chinese Chemical Letters, vol. 20, no. 8, pp. 955–957, 2009. View at Publisher · View at Google Scholar · View at Scopus
  42. H. Guinaudeau and M. Shamma, “The protopine alkaloids,” Journal of Natural Products, vol. 45, no. 3, pp. 237–246, 1982. View at Publisher · View at Google Scholar · View at Scopus
  43. M. Iranshahy, R. J. Quinn, and M. Iranshahi, “Biologically active isoquinoline alkaloids with drug-like properties from the genus Corydalis,” RSC Advances, vol. 4, no. 31, pp. 15900–15913, 2014. View at Publisher · View at Google Scholar · View at Scopus
  44. X.-Y. Cheng, Y. Shi, S.-L. Zheng, H. Sun, and W. Jin, “Studies on chemical constituents in the anti-myocardial ischemia effective fraction of Corydalis yanhusuo,” Journal of Chinese Medicinal Materials, vol. 31, no. 11, pp. 1656–1658, 2008. View at Google Scholar · View at Scopus