Development and Validation of a Stability-Indicating HPLC Method for the Simultaneous Determination of Florfenicol and Flunixin Meglumine Combination in an Injectable Solution

Table 3

The results of stress testing of Flr and Flx under various conditions.

Stress type	Detectable change	Degradation
		Name	Percentage
Basic hydrolysis	26% florfenicol assay loss; Degradation	Fr1; Fr2	23.0%; 4.5%
Acid hydrolysis	10.5% florfenicol assay loss; Degradation	Fr3	11.0%
Oxidative/solution	61% flunixin assay loss; Degradation	Fx1	14.5%
Thermal	7.5% florfenicol assay loss; Degradation	Fr4	8.0%
Photodegradation	No change