Research Article
Evaluation of Global Genomic DNA Methylation in Human Whole Blood by Capillary Electrophoresis UV Detection
Table 1
Interassay precision of the quality control samples calf thymus DNA or human leukocyte (HL) of our CE method compared to other published values.
| Interassay CV% | Sample | Analytical method | Reference |
| 3.5 | Calf thymus | HPLC-ESI-MS/MS | [12] | 5.7 | HL DNA | HPLC-ESI-MS/MS | [13] | 5.58–6.06 | HL DNA | HPLC-MS/MS | [14] | 4.92 | HL DNA | HPLC-MS/MS | [15] | 3.8 | Calf thymus | HPLC-UV | [16] | 15 | Calf thymus | HPLC-UV | [17] | <4 | Calf thymus | UPLC-UV | [18] | <15 | HL DNA | GC-MS | [19] | 7 | Calf thymus | GC-MS | [20] | 6.5a | Calf thymus | GC-MS | [21] | 3.0 | Calf thymus | GC-FID | [22] | 8.2a | Calf thymus | GC-ECD | [23] | <5 | Calf thymus | CE-LIF | [24] | <5 | Calf thymus | CE-UV | [25] | 3.2 | HL DNA | CE-UV | [26] | 3.3 | HL DNA | CE-UV | [27] | 1.98 | HL DNA | CE-UV | Our method |
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aData published in mol% are converted to 5-methylcytosine/total cytosine ratio.
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