Development and Validation of a Chromatography Method Using Tandem UV/Charged Aerosol Detector for Simultaneous Determination of Amlodipine Besylate and Olmesartan Medoxomil: Application to Drug-Excipient Compatibility Study

Table 2

Precision and accuracy for AMLO and OLME determined by HPLC-DAD and HPLC-CAD.

	Concentration added (μg mL^−1)	DAD (n = 5)			CAD (n = 5)
		Recovery (%)	RSD intraday (%)	RSD interday (%)	Recovery (%)	RSD intraday (%)	RSD interday (%)
AMLO	20	95.46	0.54	0.96	95.52	0.57	0.88
	40	101.85	0.56	0.81	100.72	0.49	0.85
	80	100.31	0.42	0.68	99.45	0.51	0.91
OLME	50	99.34	0.48	0.89	99.22	0.52	0.93
	100	100.66	0.45	0.87	100.89	0.43	0.84
	150	97.92	0.39	0.67	99.72	0.42	0.89

n: number of replicates.