UPLC-Tandem Mass Spectrometry Method for Simultaneous Determination of Fluoxetine, Risperidone, and Its Active Metabolite 9-Hydroxyrisperidone in Plasma: Application to Pharmacokinetics Study in Rats

Table 3

Recovery data of FLX, RIS, and 9-OH-RIS (three QC samples each) in rat plasma (mean ± SD).

Analyte	Nominal conc.	Recovery (%)
FLX	1.0	92.99
	100.0	87.15
	1000.0	91.48
Average		90.54
RIS	0.2	95.88
	100.0	93.79
	1000.0	99.55
Average		96.41
9-OH-RIS	0.2	91.59
	100.0	78.20
	1000.0	83.21
Average		84.34