Optimization of Extract Method for Cynomorium songaricum Rupr. by Response Surface Methodology

Table 4

Observed response in the Box-Behnken design for optimization of C. songaricum extraction formulations with predicted values generated by Design-Expert software (three variables: X₁: material-to-solvent ratio, X₂: ultrasonic time, and X₃: ultrasonic power. D: desirability function).

Formulations	Independent variables			Actual value	Predicted value
	X1	X2	X3	D	D
1	1/10	20	80	0.46	0.50
2	1/30	20	80	0.00	0.02
3	1/10	60	80	0.39	0.37
4	1/30	60	80	0.12	0.078
5	1/10	40	60	0.71	0.66
6	1/30	40	60	0.25	0.23
7	1/10	40	100	0.49	0.51
8	1/30	40	100	0.14	0.18
9	1/20	20	60	0.52	0.53
10	1/20	60	60	0.29	0.35
11	1/20	20	100	0.35	0.29
12	1/20	60	100	0.40	0.40
13	1/20	40	80	0.95	0.89
14	1/20	40	80	0.88	0.89
15	1/20	40	80	0.87	0.89
16	1/20	40	80	0.81	0.89
17	1/20	40	80	0.94	0.89