Development of an Analytical Protocol for Determination of Cyanide in Human Biological Samples Based on Application of Ion Chromatography with Pulsed Amperometric Detection

Table 3

Comparison of validation parameters for different methods of marking cyanides in biological materials samples.

	Sample	Linear range		LOD	Recovery [%]	Run time [min]	References
IC-PAD	Urine	1–100 μg/L	0.992	1.8 μg/L	80	25	Present work
	Saliva	5–100 μg/L	0.994	5.2 μg/L	113
	Sweat	3–100 μg/L	0.993	5.8 μg/L	88
GC-MS	Plasma urine	20–100000 μg/L	0.998	40 μg/L	90.58–115.56	25	[16]
Spectrophotometric method	Blood			60 μg/L			[7]
GC-MS	Blood	0.02 µM/L		0.1 µM/mL	80		[12]
IC-UV/Vis	Blood	3.8–7690 pM/mL		3.8 pM/mL	83		[17]
Spectrophotometric method	Nasal discharge		0.995	2 μg/L			[11]

data.