Determination of Epimedin B in Rat Plasma and Tissue by LC-MS/MS: Application in Pharmacokinetic and Tissue Distribution Studies

Figure 3

Representative MRM chromatograms: (A1) blank plasma, (A2) blank plasma spiked with epimedin B at LOQ, (A3) rat plasma sample obtained at 0.5 h after administration, (A4) blank plasma spiked with IS, (B1) blank liver, (B2) blank liver spiked with epimedin B at LOQ, (B3) rat liver sample obtained at 0.5 h after administration, and (B4) blank liver spiked with IS.