Research Article
Determination of Epimedin B in Rat Plasma and Tissue by LC-MS/MS: Application in Pharmacokinetic and Tissue Distribution Studies
Table 1
Regression equations of epimedin B in rat plasma and tissue samples (
).
| | Sample | Equation | | Linear range (ng/mL) |
| | Plasma | Y = 0.0049X + 0.0012 | 0.9927 | 1–500 | | Liver | Y = 0.0045X + 0.0011 | 0.9969 | 1–500 | | Heart | Y = 0.0045X + 0.0005 | 0.9974 | 1–500 | | Spleen | Y = 0.0042X + 0.0007 | 0.9941 | 1–500 | | Lung | Y = 0.0049X + 0.0009 | 0.9957 | 1–500 | | Kidney | Y = 0.0036X + 0.0006 | 0.9967 | 1–500 | | Brain | Y = 0.0031X + 0.0005 | 0.9969 | 1–500 | | Ovary | Y = 0.0045X + 0.0011 | 0.9969 | 1–500 | | Womb | Y = 0.0045X + 0.0011 | 0.9969 | 1–500 |
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