Determination of Epimedin B in Rat Plasma and Tissue by LC-MS/MS: Application in Pharmacokinetic and Tissue Distribution Studies

Table 4

Stability of epimedin B in plasma and tissue samples ().

Matrix	Conc.; ng/mL	Mean ± SD
		Bench-	Freeze-	Auto	Long-
Plasma	2
	20
	400
Liver	2
	20
	400
Heart	2
	20
	400
Spleen	2
	20
	400
Lung	2
	20
	400
Kidney	2
	20
	400
Brain	2
	20
	400
Ovary	2
	20
	400
Womb	2
	20
	400

least 6 h at room temperature. least 3 freeze-thaw cycles. least 24 h at 4°C. least 4 weeks at °C.