Research Article
A Pyridazine-Based Fluorescent Probe Targeting Aβ Plaques in Alzheimer’s Disease
Table 1
Fluorescence profile and KD and log P values of probe 3 with Aβ aggregates.
| Optical properties | Probe 3 |
| λex (nm) | 408 | λem (nm) | 670 | λex/λem with Aβ (nm) | 408/604 | Fold increase with Aβ | 34.92 | KD (mean ± SD) (µM) | 0.35 ± 0.03 | log P (lipophilicity) | 2.94 |
|
|