A Stability Indicating HPLC Assay Method for Analysis of Rivastigmine Hydrogen Tartrate in Dual-Ligand Nanoparticle Formulation Matrices and Cell Transport Medium

Table 5

Accuracy data for RHT in NPs matrix, release medium, and cell transport medium.

Prepared RHT concentration (µg/mL)	RHT in NPs matrix		RHT in release medium		RHT in cell transport medium
	Measured concentration (µg/mL)	Recovery (%)	Measured concentration (µg/mL)	Recovery (%)	Measured concentration (µg/mL)	Recovery (%)
0.50	0.49 ± 0.13	98.0 ± 0.2	0.49 ± 0.11	98.4 ± 0.1	0.49 ± 0.16	98.6 ± 0.2
2.00	1.99 ± 0.16	99.5 ± 0.3	2.01 ± 0.10	100.5 ± 0.3	2.00 ± 0.12	99.8 ± 0.2
4.00	3.96 ± 0.19	99.0 ± 0.3	4.04 ± 0.24	101.0 ± 0.2	3.95 ± 0.31	98.7 ± 0.3
6.00	5.97 ± 0.11	99.5 ± 0.1	5.95 ± 0.25	99.2 ± 0.2	5.93 ± 0.15	98.8 ± 0.2
8.00	8.03 ± 0.16	100.4 ± 0.3	7.98 ± 0.19	99.8 ± 0.6	7.97 ± 0.16	99.6 ± 0.2
10.00	9.99 ± 0.37	99.9 ± 0.2	9.99 ± 0.15	99.9 ± 0.2	9.98 ± 0.24	99.8 ± 0.1
	Mean ± SD = 99.4 ± 0.8		Mean ± SD = 99.8 ± 0.9		Mean ± SD = 99.2 ± 0.9