Journal of Analytical Methods in Chemistry

Research Article

Further Validation of a Rapid Screening Semiquantitative Thin-Layer Chromatographic Method for Marketed Antimalarial Medicines for Adoption in Malawi

Table 4

Comparison of quality of some antimalarial medicines by SQ-TLC and HPLC.
CodeManufacturer’s label claim (mg)SQ-TLC resultsHPLC results
Quality of individual API components in the order presented in label claimQuality of the sample as a wholeQuality of individual API components in the order presented in label claimQuality of the sample as a whole
24Y13ATS/SDX/PYR: 100/500/25BLCNCCNCCNCCNC
2X15ATM/LUM: 20/120NCCNCNCCNC
24X14ATM/LUM: 20/120NCNCNCNCNCNC
12X14ATM/LUM: 20/120NCCNCNCCNC
23Z1DHA/SDX/PYR: 60/500/25NCCCNCNCCCNC
23Z1DHA/SDX/PYR: 60/500/25NCCCNCNCCCNC
14P10SDX/PYR: 500/25NCCNCNCCNC
13Z1DHA/SDX/PYR: 60/500/25NCBLCCNCNCNCCNC
35Z1DHA/SDX/PYR: 60/500/25NCBLCCNCNCNCCNC
16Z1DHA/PPQ: 40/320C—CC—C
11V5QUN: 50 mg/5 mLCCC—C
4V5QUN: 50 mg/5 mLBLCBLCBLCBLC
42Y12ATS/SM/PYR: 200/500/25C—CCC—NCNC
19X1ATM/LUM: 80/480CBLCBLCCNCNC
21X1ATM/LUM: 20/120CBLCBLCCNCNC
11P2SDX/PYR: 500/25BLCBLCBLCNCNCNC
12Z3DHA/PPQ: 40/320BLC—BLCNC—NC
12V5QUN: 50 mg/5 mLBLCBLCNCNC
13V5QUN: 50 mg/5 mLCCBLCBLC