Screening and Characterizing Tyrosinase Inhibitors from Salvia miltiorrhiza and Carthamus tinctorius by Spectrum-Effect Relationship Analysis and Molecular Docking
Table 2
Correlation coefficients between chromatogram peaks and inhibition rates.
Peak number
1
2
3
4
5
6
7
8
9
10
11
12
13
Inhibition rate
0.940
−0.702
−0.695
−0.501
−0.753
−0.769
−0.677
0.812
−0.721
−0.775
−0.790
−0.351
0.807
Peak number
14
15
16
17
18
19
20
21
22
23
24
25
26
Inhibition rate
0.510
−0.878
−0.742
−0.632
−0.713
0.714
0.919
−0.746
0.903
−0.129
−0.615
−0.233
−0.623
Peak number
27
28
29
30
31
32
33
34
35
36
37
38
39
Inhibition rate
0.952
−0.544
0.908
0.650
0.900
−0.397
−0.015
−0.466
0.321
−0.824
−0.795
−0.726
−0.762
Peak number
40
41
42
43
44
45
46
47
48
49
50
51
52
Inhibition rate
0.892
−0.571
−0.790
−0.785
−0.867
−0.745
0.891
−0.640
−0.746
−0.708
0.135
−0.753
−0.451
Peak number
53
54
55
56
57
58
59
60
61
62
63
64
65
Inhibition rate
−0.627
−0.943
−0.929
−0.759
−0.778
−0.037
−0.769
0.591
−0.621
−0.741
0.786
0.824
−0.725
Peak number
66
67
68
69
70
71
72
73
74
75
76
77
78
Inhibition rate
−0.667
−0.772
0.596
0.618
0.124
0.704
−0.712
0.654
0.887
0.215
0.361
0.371
0.718
Peak number
79
80
81
82
83
84
85
86
Inhibition rate
0.610
0.646
−0.733
0.565
−0.717
0.279
−0.123
−0.512
Note. Pearson correlation, “r” represents the relevant strength; means Very significant correlation.