Multiresidue Method for Quantification of Sulfonamides and Trimethoprim in Tilapia Fillet by Liquid Chromatography Coupled to Quadrupole Time-of-Flight Mass Spectrometry Using QuEChERS for Sample Preparation

Table 3

Intraday and interdays precision of sulfonamides and trimethoprim.

Validation parameters	Sulfonamides and trimethoprim
	SP	STZ	SMZ	SDMX	SMX	SMPD	SMR	TMP
Intraday precision (CV%)
10 ng·g^−1	12.8	11.7	11.6	7.7	6.4	7.1	11.3	8.3
20 ng·g^−1	11.2	8.2	8.3	7.7	5.9	13.9	13.6	7.8
40 ng·g^−1	12.9	14.9	15.0	12.3	7.9	6.1	14.5	10.6
Interdays precision (CV%)
10 ng·g^−1	14.4	19.2	19.4	17.8	11.9	9.4	15.4	13.2
20 ng·g^−1	19.3	17.2	11.8	3.4	4.2	9.0	16.7	17.7
40 ng·g^−1	19.0	18.6	19.1	4.5	10.0	5.5	15.0	16.2

SP, sulfapyridine; STZ, sulfathiazol; SMZ, sulfamethazine; SDMX, sulfadimethoxine; SMX, sulfamethoxazole; SMPD, sulfamethoxypyridazine; SMR, sulfamerazine; TMP, trimethoprim; CV, coefficient of variation.