Research Article
Pharmacokinetics of Eight Flavonoids in Rats Assayed by UPLC-MS/MS after Oral Administration of Drynariae rhizoma Extract
Table 1
Precursor ion and product ion transition and parameters of the analytes used in this study.
| | Analytes | Retention time (min) | Precursor ion species | MRM transition | Cone (V) | Collision (V) | Dwell time (ms) | | Precursor ion | Product ion |
| | Neoeriocitrin | 2.12 | [M + H]+ | 597.5 | 289.2 | 25 | 30 | 0.2 | | Luteolin-7-O-β-D-glucoside | 2.33 | [M + H]+ | 449.1 | 287.1 | 20 | 20 | 0.2 | | Astragalin | 2.62 | [M + H]+ | 449.1 | 287.1 | 30 | 30 | 0.2 | | Naringin | 2.73 | [M + H]+ | 581.5 | 273.2 | 20 | 25 | 0.2 | | Eriodictyol | 3.34 | [M + H]+ | 289.2 | 153.1 | 30 | 25 | 0.2 | | Luteolin | 3.63 | [M + H]+ | 287.1 | 153.1 | 30 | 30 | 0.2 | | Naringenin | 4.29 | [M + H]+ | 273.2 | 153.1 | 20 | 30 | 0.2 | | Kaempferol | 4.41 | [M + H]+ | 287.1 | 153.1 | 30 | 30 | 0.2 | | Quercetin (IS) | 3.42 | [M + H]+ | 303.2 | 153.1 | 20 | 25 | 0.2 |
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