Pharmacokinetics of Eight Flavonoids in Rats Assayed by UPLC-MS/MS after Oral Administration of Drynariae rhizoma Extract

Table 2

Regression data, LLOQ, and LLOD of eight analytes.

Analytes	Calibration curves	Correlation coefficient	Linear range (ng/ml)	LLOQ (ng/ml)	LLOD (ng/ml)
Neoeriocitrin	y = 0.132x + 11.60	0.9996	3.75–3749	3.75	0.94
Luteolin-7-O-β-D-glucoside	y = 12.48x + 339.3	0.9994	1.86–4230	1.86	0.62
Astragalin	y = 28.87x + 287.0	0.9992	1.32–1400	1.32	0.33
Naringin	y = 6.032x + 635.9	0.9991	1.24–6370	1.24	0.41
Eriodictyol	y = 35.71x + 258.9	0.9993	0.14–1040	0.14	0.05
Luteolin	y = 12.21x + 434.0	0.9990	2.74–3780	2.74	0.91
Naringenin	y = 6.269x + 128.9	0.9991	0.12–1210	0.12	0.3
Kaempferol	y = 7.25x − 79.66	0.9991	5.33–1209	5.33	1.78