Research Article

Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD

Figure 1

Representative chromatograms obtained from the analysis of human plasma using (a) procedure (A), PP with aqueous TCA; (b) procedure (B), PP with a mixture of acetonitrile and ammonia (90  :  10); and (c) procedure (C), SPE cleanup with Oasis MCX. Insets: zoom of the ADMA and SDMA peaks at 18.1 and 19.0 min, respectively.
(a)
(b)
(c)