Research Article

Establishing Analytical Performance Criteria for the Global Reconnaissance of Antibiotics and Other Pharmaceutical Residues in the Aquatic Environment Using Liquid Chromatography-Tandem Mass Spectrometry

Table 3

Percent false negatives in spiked environmental matrices at different tolerance ranges for 23 compounds without tetracyclines and quinolones.

Tolerance rangeMatrixOverall false negatives
InfluentEffluentDownstreamUpstream

±10%48%42%41%35%31%
±20%20%13%10%8%10%
±30%8%4%2%2%4%
±40%4%2%0%0%2%
±50%2%1%0%0%1%