Establishing Analytical Performance Criteria for the Global Reconnaissance of Antibiotics and Other Pharmaceutical Residues in the Aquatic Environment Using Liquid Chromatography-Tandem Mass Spectrometry

Table 4

Percent false negatives for tetracyclines and quinolones at the 50% tolerance range in spiked environmental matrices.

Compounds	Matrix				Overall false negatives
	Influent	Effluent	Downstream	Upstream
Chlortetracycline	10%	0%	0%	0%	2%
Ciprofloxacin	96%	71%	33%	13%	61%
Enrofloxacin	5%	0%	0%	0%	1%
Norfloxacin	0%	4%	0%	0%	1%
Oxytetracycline	0%	30%	29%	22%	21%
Sarafloxacin	12%	16%	0%	20%	13%
Tetracycline	11%	0%	0%	0%	3%