Establishing Analytical Performance Criteria for the Global Reconnaissance of Antibiotics and Other Pharmaceutical Residues in the Aquatic Environment Using Liquid Chromatography-Tandem Mass Spectrometry

Table 7

Compounds with ion ratios detected outside the set tolerance range of ±40% for WWTP influent samples and 30% for WWTP effluent, upstream, and downstream samples.

Matrix	Compound	Tolerance range	Calculated ion ratio
Effluent	Acetylsulfamethoxazole	0.88–1.64	1.74
	Azithromycin	1.89–3-5	1.86
Downstream	Clarithromycin	1.28–2.38	2.41
	Clarithromycin	1.28–2.38	2.42
Upstream	Azithromycin	1.89–3-5	1.74