Development and Validation of a Versatile UPLC-PDA Method for Simultaneous Determination of Paracetamol, Tizanidine, Aceclofenac, and Nimesulide in Their New Combinations

Table 4

Intra- and interday precision results for the proposed UPLC method.

Analyte	Concentration taken (g·mL^−1)		Concentration found (g·mL^−1)	Recovery (%)	Intraday		Interday
					Recovery (%)	RSD (%)	Recovery (%)	RSD (%)
PAR	QCL	195	193.34	99.15	99.03	0.45	99.03	0.36
	QCM	260	257.72	99.12	98.28	0.13	98.28	0.45
	QCH	390	384.44	98.57	98.38	0.37	98.38	0.67
TIZ	QCL	1.2	1.19	99.13	98.51	0.62	98.57	0.12
	QCM	1.6	1.60	99.93	99.01	0.77	99.00	0.32
	QCH	2.4	2.36	98.51	98.74	0.89	98.47	0.36
ACF	QCL	60	58.96	98.27	97.49	0.56	99.81	0.52
	QCM	80	78.66	98.33	97.70	0.20	98.61	1.25
	QCH	120	118.26	98.55	97.91	0.23	97.52	0.37
NIM	QCL	60	59.30	98.84	101.26	0.34	101.30	0.60
	QCM	80	98.60	98.56	101.16	0.56	100.79	0.36
	QCH	120	98.33	98.33	100.23	0.94	100.10	0.53

Average of three determinations.