NMR, Novel Pharmacological and In Silico Docking Studies of Oxyacanthine and Tetrandrine: Bisbenzylisoquinoline Alkaloids Isolated from Berberis glaucocarpa Roots

Table 2

¹H NMR (400 MHz) and¹³C NMR (100 MHz) data of compound 2 (CDCl₃).

Position	δH in ppm (mult., J in Hz)	δC in ppm	Position	δH in ppm (mult., J in Hz)	δC in ppm
1	3.73, (m)	61.51	1/	3.85, (m)	62.84
N-Me	2.28, (s)	43.01	N/-Me	2.59, (s)	42.56
3	2.85 and 3.39, (m)	44.08	3/	2.82 and 3.42, (m)	44.78
4	2.36 and 2.87, (m)	21.92	4/	2.67 and 2.90, (m)	25.69
4a	—	128.02	4/a	—	127.31
5	6.27, (s)	105.46	5/	6.49, (s)	112.10
6	—	151.09	6/	—	149.10
7	—	136.91	7/	—	143.11
6-OMe	3.73, (s)	55.55	6/-OMe	3.37, (s)	55.57
7-OMe	3.15, (s)	60.04
8	—	147.80	8/	5.98, (br.s)	119.98
8a	—	122.74	8/a	—	128.34
α	2.42 and 2.66, (m)	40.86	α/	2.68 and 3.25, (m)	38.07
9	—	133.51	9/	—	135.12
10	6.51, (d, 2.2)	116.27	10/	6.28 (dd, 8.2, 2.2)	131.95
11	—	149.51	11/	6.77, (dd, 8.4, 2.4)	121.18
12-OMe	3.85, (s)	55.91	12/	—	153.72
12	—	146.88
13	6.80, (d, 8.2)	111.31	13/	7.14, (dd, 8.4, 2.3)	121.81
14	6.86, (dd, 8.4, 2.2)	123.07	14^/	7.35, (dd, 8.4, 2.3)	129.95