Analytical Method Development and Validation for the Quantification of Acetone and Isopropyl Alcohol in the Tartaric Acid Base Pellets of Dipyridamole Modified Release Capsules by Using Headspace Gas Chromatographic Technique

<table class="table-group" id="tab7"><tr><td><table class="table"><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Description</td><td class="align_center" colspan="2">Dipyridamole and known impurities</td></tr><tr class="thead"><td class="align_center">Acetone</td><td class="align_center">Isopropyl alcohol</td></tr><tr><td class="thead-hr" colspan="3"><hr/></td></tr><tr><td class="align_left">Square of correlation coefficient (<i>R</i><sup>2</sup>)</td><td class="align_center">0.998</td><td class="align_center">0.997</td></tr><tr><td class="align_left">Slope</td><td class="align_center">1385.9</td><td class="align_center">357.7</td></tr><tr><td class="align_left"><i>Y</i>-intercept</td><td class="align_center">100,186.4</td><td class="align_center">39,555.8</td></tr><tr><td class="align_left">% <i>Y</i>-intercept</td><td class="align_center">1.4</td><td class="align_center">2.1</td></tr><tr class="table-tr"><td colspan="3"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Linearity data of acetone and isopropyl alcohol.</div>

Journal of Analytical Methods in Chemistry

tab7

Table 7

Table 7: Analytical Method Development and Validation for the Quantification of Acetone and Isopropyl Alcohol in the Tartaric Acid Base Pellets of Dipyridamole Modified Release Capsules by Using Headspace Gas Chromatographic Technique 

Table 7 | Analytical Method Development and Validation for the Quantification of Acetone and Isopropyl Alcohol in the Tartaric Acid Base Pellets of Dipyridamole Modified Release Capsules by Using Headspace Gas Chromatographic Technique 