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Journal of Analytical Methods in Chemistry
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Journal of Analytical Methods in Chemistry
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2018
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Article
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Tab 5
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Research Article
Determination of Fluoroquinolones in Pharmaceutical Formulations by Extractive Spectrophotometric Methods Using Ion-Pair Complex Formation with Bromothymol Blue
Table 5
The effect of excipients on the determination of fluoroquinolones (10
µ
g/mL).
Recovery (%) ± SD
Excipients
Amount of excipient added (
μ
g/mL)
Ofloxacin
Levofloxacin
Ciprofloxacin
Magnesium stearate
500
102.04 ± 0.12
101.23 ± 0.089
98.53 ± 0.91
Glucose
250
100.17 ± 0.16
99.04 ± 0.14
99.08 ± 0.062
Lactose
500
99.92 ± 0.21
100.20 ± 0.12
99.73 ± 0.21
Starch
200
100.96 ± 0.24
98.89 ± 0.13
101.31 ± 0.17
Sodium chloride
500
100.13 ± 0.24
100.15 ± 0.11
99.75 ± 0.16