A Simple Separation Method of the Protein and Polystyrene Bead-Labeled Protein for Enhancing the Performance of Fluorescent Sensor

Figure 2

Simulation for separating the molecules by DEP force in the two microholes. (a) Distribution of at the top view of the electrode. The diameter of the small microhole and pitch between two microholes were represented as “d” and “p,” respectively. (b) According to the applied voltage, maximum intensity of occurring in the 3 μm hole increased, whereas molecular weight of the protein, allocated into the microhole, decreased. (c) Maximum intensity of in the other microhole and the diameter of PS beads, allocated into the hole, decreased according to the increase of the diameter.

(a)

(b)

(c)