Research Article

A Localized Surface Plasmon Resonance Sensing Method for Simultaneous Determination of Atenolol and Amiloride in Pharmaceutical Dosage Forms and Urine Samples

Table 4

Determination of ATN and AML in laboratory-prepared mixtures.

Added amount (mol·L−1)Found amount (mol·L−1)Recovery (%)# ± SD
ATN (×10−5)AML (×10−6)ATN (×10−5)AML (×10−6)

110.980.9998.0 ± 1.299.1 ± 0.9
221.922.0196.0 ± 0.8100.5 ± 0.7
443.893.9397.3 ± 0.798.3 ± 0.4
666.105.88101.7 ± 0.598.0 ± 0.9
887.797.9297.4 ± 0.499.0 ± 0.6
101010.209.73102.0 ± 0.297.3 ± 0.1

ATN is measured at 274 nm. AML is measured at 364.5 nm. #Average of three determinations ± SD.