A Localized Surface Plasmon Resonance Sensing Method for Simultaneous Determination of Atenolol and Amiloride in Pharmaceutical Dosage Forms and Urine Samples

Table 6

A comparison between different approaches used for simultaneous determination of ATN and AML.

Method	Limit of detection (µg·mL^−1)	Linearity range (µg·mL^−1)			Ref.
	ATN	AML	ATN	AML
HPLC	1.38 × 10^−3	1.4 × 10^−5	5–50	0.25–2.5	[3]
HPLC	3 × 10^−3	4 × 10^−3	40–160	2–8	[4]
Electrophoresis	3 × 10^−3	4 × 10^−3	5–250	5–250	[5]
Electrophoresis	0.6	0.5	0.6–10	0.5–10	[6]
UV spectrophotometry	0.111	0.033	15–30	1.25–5	[7]
Spectrofluorimetry	5.9	2.8	5.6–280	10–400	[8]
This method	2.37	0.096	2.66–26.6	0.22–2.29