Development of Micellar HPLC-UV Method for Determination of Pharmaceuticals in Water Samples

Table 2

Chromatographic resolutions obtained in the factorial design.

Factorial design	Rs (1-2)	Rs (2-3)	Rs (3-4)	Rs (4-5)	Rs (5-6)	Rs (6-8)	Rs (8-9)	Rs (9-10)	Rs (10-7)
1	7.17	5.98	1.27	0.53	9.89	1.62	2.75	1.37	1.58
2	6.39	6.60	0.96	0.98	14.11	0.00	3.42	1.40	2.83
3	6.77	5.98	0.85	1.59	9.07	3.66	1.30	1.06	1.24
4	6.64	6.58	2.18	1.69	8.70	2.10	1.55	1.45	2.33
5	7.04	5.33	1.99	0.00	13.44	0.00	2.01	1.42	2.49
6	6.90	5.61	1.06	1.36	10.08	1.30	1.41	1.23	2.81
7	6.99	4.89	1.85	1.08	9.48	1.23	1.26	1.33	2.76
8	5.78	6.26	2.49	0.51	13.53	0.92	1.22	1.47	5.16

Amoxicillin (1), caffeine (2), tetracycline (3), diclofenac (4), ibuprofen (5), 17α-ethynylestradiol (6), levonorgestrel (7), nimesulide (8), ciprofloxacin (9), and norfloxacin (10).