Development of Micellar HPLC-UV Method for Determination of Pharmaceuticals in Water Samples

Table 4

Analyte determination by the proposed and conventional methods.

Sample		Proposed method	Conventional methods
	Analyte	Concentration	Concentration
Moscados stream (μg·L^−1)	Caf	0.109 ± 0.002	0.086 ± 0.011
Cleópatra stream (μg·L^−1)	Caf	1.204 ± 0.034	1.358 ± 0.020
	Tetr	0.188 ± 0.007	0.195 ± 0.009
	Norflo	0.463 ± 0.022	0.427 ± 0.038
Borba Gato stream (μg·L^−1)	Caf	0.140 ± 0.005	0.136 ± 0.002
Mandacarú stream (μg·L^−1)	Caf	0.742 ± 0.024	0.766 ± 0.038
	Norflo	0.380 ± 0.016	0.395 ± 0.011
Morangueiro stream (μg·L^−1)	Caf	0.367 ± 0.020	0.371 ± 0.014
	Cipro	0.295 ± 0.010	0.281 ± 0.019
Maringá stream (μg·L^−1)	Caf	0.173 ± 0.010	0.190 ± 0.012
Potable water (μg·L^−1)	Caf	0.071 ± 0.003	0.064 ± 0.007

The conventional methods used were as follows: tetracycline [18]; ibuprofen, diclofenac, and nimesulide [24]; levonorgestrel and 17α-ethynylestradiol [25]; caffeine [29]; ciprofloxacin and norfloxacin [30]; amoxicillin [31].