Simultaneous Determination of Over-the-Counter Pain Relievers in Commercial Pharmaceutical Products Utilizing Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) Multivariate Calibration Model

Table 3

Figures of merits of the calibration set for the developed MCR-ALS model.

Parameters	PAR	ASA	CAF	NPX	IPF
Calibration range	0.5–7	1–15	0.5–3	0.5–3.5	1–15
Slope	1.0000	0.9999	1.0000	1.0000	0.9999
Intercept	8.75 × 10^−15	−1.96 × 10^−14	−2.02 × 10^−13	2.51 × 10^−3	2.13 × 10^−3
RMSECV	0.136	0.045	0.194	0.152	0.064
SEP	0.153	0.032	0.170	0.149	0.063
Bias	2.64 × 10^−2	4.12 × 10^−3	−2.58 × 10^−2	3.22 × 10^−2	3.11 × 10^−3
RE (%)	1.32	0.94	1.65	1.28	1.15
Coefficient of determination (r^2)	0.9998	0.9995	0.9993	0.9998	0.9996