Quantitative Characteristics of Toxic Compounds According to the Solvent Type

Table 4

Experimental results for three target compounds (benzene, toluene, and MIT) based on four different solvents (MeOH, hexane, PBS, and DMSO), including the response factor (RF, ng⁻¹), normalized-RF (N-RF, ng⁻¹/ng⁻¹), determination of correlation (R²), relative standard deviation (RSD, %), and limit of detection (LOD, ng).

Solvent	Factors	Target compound
		Benzene	Toluene	MIT
MeOH	RF (ng^−1)	26,164	43,618	7,877
	N-RF^a (ng^−1/ng^−1)	0.79	0.55	0.87
	R^2	0.9978	0.9984	0.9994
	RSD (%)	0.83	0.72	5.56
	LOD (ng)	0.02	0.01	0.07
Hexane	RF (ng^−1)	33,674	78,604	1,117
	N-RF (ng^−1/ng^−1)	1	1	0.12
	R^2	0.9630	0.9969	0.0562
	RSD (%)	4.22	2.35	10.6
	LOD (ng)	0.01	0.00	0.18
PBS	RF (ng^−1)	11,286	21,026	9,067
	N-RF (ng^−1/ng^−1)	0.34	0.27	1
	R^2	0.9788	0.9801	0.9997
	RSD (%)	16.2	14.6	2.41
	LOD (ng)	0.01	0.01	0.01
DMSO	RF (ng^−1)	31,932	60,147	8,148
	N-RF (ng^−1/ng^−1)	0.95	0.77	0.90
	R^2	0.9984	0.9995	0.9998
	RSD (%)	7.69	10.4	6.19
	LOD (ng)	0.02	0.01	0.08

^aNormalized-RF (N-RF): RF value/maximum RF among four different solvents.