Comparative Pharmacokinetic Studies of Four Ginsenosides in Rat Plasma by UPLC-MS/MS after Oral Administration of Panax quinquefolius-Acorus gramineus and Panax quinquefolius Extracts

Table 4

Recoveries and matrix effects of the ginsenosides in rat plasma.

Compound	Concentration (ng/mL)	Extraction recovery		Matrix effect
		Mean (%)	RSD (%)	Mean (%)	RSD (%)
Rb1	7.2	77.51	6.31	93.37	8.12
	142.4	85.73	1.52	98.36	4.33
	911.4	76.43	13.15	90.44	8.79
Rb2	3.2	79.62	2.50	91.11	8.01
	62.5	86.89	10.74	97.83	7.52
	400.0	78.15	4.62	102.10	3.77
Rd	2.4	86.64	13.60	99.67	12.74
	48.8	95.20	10.17	100.29	8.88
	312.2	88.58	6.51	106.2	13.74
Re	5.0	82.34	6.74	102.56	11.12
	98.6	86.32	3.33	99.52	7.65
	630.8	85.79	12.10	107.11	15.02
IS	720	89.31	5.76	92.30	6.47