Coordinated Dispersion and Aggregation of Gold Nanorod in Aptamer-Mediated Gestational Hypertension Analysis

Figure 1

(a) Schematic representation of cortisol detection by aptamer-GNR based colorimetric assay. As-received GNR appears red and in the presence of NaCl, it turned into purple. At higher concentration of aptamer-GNR, it appears to be red even in the presence of NaCl. When aptamer-GNR reacts with cortisol at appropriate concentration, the color of the GNR solution is turned to purple with NaCl, indicating the release of the aptamer from the GNR. The aggregation is displayed by SEM analysis (inset). (b) Secondary structure of anticortisol aptamer. Folded by mfold online software.

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