Research Article
Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder
Table 1
Gradient program of mobile phase.
| Time (minutes) | 0.002 M solution of tetrabutylammonium sulfate (%) | Methanol (%) | Elution mode |
| 0.0–7.0 | 80 | 20 | Initial hold time | 7.0–12.5 | 80 ⟶ 50 | 20 ⟶ 50 | Linear gradient | 12.5–15.0 | 80 | 20 | Final hold time |
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