Development and Validation of an HPLC Method for Simultaneous Assay of Potassium Guaiacolsulfonate and Sodium Benzoate in Pediatric Oral Powder

Table 6

Results of system precision for potassium guaiacolsulfonate.

No. of injections	Retention time of potassium guaiacolsulfonate (minutes)		Peak area (mAu·s)		Asymmetry of peak		Number of theoretical plates		Resolution
	Peak 1	Peak 2	Peak 1	Peak 2	Peak 1	Peak 2	Peak 1	Peak 2
1	5.640	6.743	1608422	587827	0.92	0.90	2035	2909	2.2
2	5.632	6.732	1607787	588263	0.91	0.91	2030	2900	2.2
3	5.626	6.727	1607305	588068	0.93	0.91	2025	2896	2.2
4	5.614	6.709	1608476	586795	0.93	0.89	2017	2880	2.2
5	5.594	6.682	1606855	586683	0.92	0.90	2002	2857	2.2
6	5.578	6.657	1605031	586820	0.93	0.91	1991	2836	2.2
Average	5.614	6.708	1607313	587409	0.92	0.90	2017	2880	2.2
RSD (%)	0.4	0.5	0.1	0.1	0.7	0.9	0.8	1.0	0.8