Determination of Progestin Residues in Fish by UPLC-Q-TOF/MS Coupled with QuEChERS

Table 1

TOF parameters of 10 progestins.

Compounds	Formula	Exact mass	Mother ions (m/z)	Daughter ions (m/z)	RT (min)
Norethisterone	C20H26O2	298.1933	299.1981	231.1714, 281.1876	4.15
17α-hydroxyprogesterone	C21H30O3	330.2195	331.2245	313.2140, 295.200	4.64
D-methylnorethindrone	C21H28O2	312.2089	313.2142	245.1871, 295.2029	4.76
17α-hydroxyprogesterone acetate	C23H32O4	372.2301	373.2391	313.2151, 271.2095	4.87
Megestrol	C22H30O3	342.2195	343.2242	325.2208, 267.1788	5.00
Medroxyprogesterone	C22H32O3	344.2351	345.2393	123.0765, 327.2294	5.28
Chlorprogestone acetate	C23H29ClO4	404.1754	405.1806	309.1852, 267.1704	5.43
Medroxyprogesterone acetate	C24H34O4	386.2454	387.2521	327.2306, 123.0820	5.50
Melengestrol acetate	C25H32O4	396.2301	397.2343	279.1719, 337.2200	5.59
Progesterone	C21H30O2	314.2246	315.2287	109.0609, 297.2179	5.64