High-Affinity Detection of Alpha-Synuclein by Aptamer-Gold Conjugates on an Amine-Modified Dielectric Surface

<div>(a) Dose-dependent binding of alpha-synuclein on the GNP-aptamer-modified IDE sensing surface. Alpha-synuclein concentrations from 0.1 to 1000 pM were tested independently on the IDE surface. (b) Linear regression analysis with different concentrations of alpha-synuclein. The limit of detection was 10 pM. Schematic representations are shown in the figure insets.</div>

Journal of Analytical Methods in Chemistry

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Figure 5

Figure 5: High-Affinity Detection of Alpha-Synuclein by Aptamer-Gold Conjugates on an Amine-Modified Dielectric Surface 