Determination of Six Macrolide Antibiotics in Chicken Sample by Liquid Chromatography-Tandem Mass Spectrometry Based on Solid Phase Extraction

Table 4

Method validation parameters for determination of macrolide antibiotics.

Analyte	Linear equation	Correlation coefficient (r)	Limit of detection (μg·kg^−1)	Limit of quantification (μg·kg^−1)
Tylosin	y = 4.769e4x − 7.013e4	0.9942	0.5	1.8
Tilmicosin	y = 7.169e4x − 4.283e4	0.9982	0.5	1.8
Azithromycin	y = 2.081e5x + 5.737e4	0.9987	0.2	0.8
Clarithromycin	y = 3.931e5x − 9.809e4	1.0000	0.2	0.8
Roxithromycin	y = 1.599e5x − 5.39e4	0.9996	0.2	0.8
Kitasamycin	y = 1.957e5x − 3.47e4	0.9964	0.5	1.8