Determination of Six Macrolide Antibiotics in Chicken Sample by Liquid Chromatography-Tandem Mass Spectrometry Based on Solid Phase Extraction

Table 5

Analytical results of macrolide antibiotics in samples.

Sample	Analyte	Amount spiked (μg·kg^−1)	Detection value (μg·kg^−1)	Recovery (%)	RSD (%)
					Intraday	Interday
Chicken	Tylosin	2.5	2.54	101.4	3.7	7.9
		10	8.93	89.3	3.5	5.6
		50	45.61	91.2	6.7	9.6
	Tilmicosin	2.5	2.42	96.7	4.2	7.5
		10	8.59	85.9	2.5	4.6
		50	44.35	88.7	2.1	4.5
	Azithromycin	1	0.82	82.1	5.6	9.8
		5	4.45	88.9	2.3	6.3
		20	16.92	84.6	3.9	8.1
	Clarithromycin	1	0.97	97.0	3.4	5.2
		5	4.09	82.8	5.9	10.6
		20	18.08	90.4	1.7	3.5
	Roxithromycin	1	0.87	87.4	4.1	7.1
		5	0.50	100.1	3.8	8.2
		20	16.70	83.6	5.1	10.3
	Kitasamycin	2.5	2.31	92.3	3.5	6.9
		10	8.61	86.1	5.1	11.1
		50	43.90	87.8	2.7	7.1