Pharmacological Evaluation of Secondary Metabolites and Their Simultaneous Determination in the Arabian Medicinal Plant Plicosepalus curviflorus Using HPTLC Validated Method

Table 2

Anti-inflammatory activity of PCME and P1, P2, and P3.

^aSample name	% decrease in oxidative stress	iNOS inhibition (IC50; µg/mL)	NF-kB inhibition (IC50; µg/mL)
PCME	66	NA	NA
P1	52	48	NA
P2	39	>50	NA
P3	57	NA	NA
Quercetin (50 µM)^b	75	—	—
Parthenolide^b	—	0.35 ± 0.22	0.5 ± 0.21

^aAt 500 µg/mL for the extract and 250 µg/mL for pure compounds. ^bPositive control. NA = no activity up to 100 µg/mL (NF-kB, iNOS) and 500 µg/mL (oxidative stress).